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Did You Know?

PMID 12237496Holmes M, Maysinger D, Foerster A, Pertens E, Barlas C, Diamond J.Neotrofin, a novel purine that induces NGF-dependent nociceptive nerve sprouting but not hyperalgesia in adult rat skin.

PMID 12605287 It stimulates release of nerve growth factors and enhances survival of neurons in the brain,Rathbone MP, Middlemiss PJ, Crocker CE, Glasky MS, Juurlink BH, Ramirez JJ, Ciccarelli R, Di Iorio P, Caciagli F.AIT-082 as a potential neuroprotective and regenerative agent in stroke and central nervous system injury.

PMID 16507305 and is under development as a potential treatment for neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and stroke.Potkin SG, Alva G, Keator D, Carreon D, Fleming K, Fallon JH.

PMID 14664808Jiang S, Khan MI, Middlemiss PJ, Lu Y, Werstiuk ES, Crocker CE, Ciccarelli R, Caciagli F, Rathbone MP.

PMID 10818529Yan R, Nguyen Q, Gonzaga J, Johnson M, Ritzmann RF, Taylor EM.

PMID 15298067NootropicsPurinesAmidesAromatic aminesBenzoic acids.